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The text begins with an introduction to a meeting led by Dr. Hawkins and Derek Bonner, a member of the AV support team, welcoming attendees to the 178th meeting of the Vaccines and Related Biological Products Advisory Committee, held on January 26, 2023. Dr. Peter Marks, the director, thanks everyone for joining and informs them that Dr. Arnold Monto will be unavailable to chair the meeting due to unforeseen circumstances. The meeting is set to proceed with these updates shared.