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Dr. Rishi Desai from Osmosis shares three key tips for taking an effective patient history. While the mechanics involve gathering a chief complaint, history of present illness (HPI), past medical history, medications, allergies, family history, social history, and a review of systems, the focus is on how to enhance the process. His first tip emphasizes the importance of listening well and showing empathy, as patients seek connection and understanding, not just mechanical questioning. The goal is to create an environment where patients feel comfortable sharing their concerns, highlighting the human element in patient care.