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the urine drug test is used for pre-employment medicals mainly because of its wider window period of testing the oral fluid test detects more recent use and therefore is more relevant when the employee is already employed its important to remember that the initial test is just a screening test which detects drug classes and not specific drugs and therefore a decision should not be made based on this we can only say that the drug test is a negative test or a non-negative test so the non-negative samples should be sent to the laboratories for more confirmatory lcms and gcms testing which detects specific drugs and is very accurate the cut-off levels for each specific drug class must be exceeded before being considered to be a non-negative or a positive for gcms you