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Motor Neurone Disease (MND) affects about 5,000 people in the UK at any given time. It encompasses a group of conditions that impair motor neurons, the nerves responsible for transmitting messages from the brain and spinal cord to muscles, leading to movement loss, weakness, and muscle wasting. Early symptoms can include mild weakness, clumsiness, tripping, or slurred speech, but the disease manifests differently in each person, complicating diagnosis. There are no definitive tests; diagnosis typically involves ruling out other conditions and monitoring symptom progression. While there is no cure for MND, specialized support services can help manage symptoms and maintain independence, ultimately improving the quality of life for those affected.