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rova tea was billed as a stem-cell directed therapy that was going to revolutionize small cell lung cancer its an antibody drug conjugates and its directed against dll 3 which was supposed to be a stem cell marker I think what were seeing is that that hypothesis has been proven to be false first of all the staining is far too common across the tumor for it to be stem cells secondly it carried with it an awful lot of toxicity including edema a lot of photosensitive skin rash weve already seen a number of negative R over T studies and this was if you like the you know the the perhaps the last nail in the coffin this was combining Rover T with platinum etoposide in the untreated patient population surprising it actually wasnt that badly tolerated but the efficacy was no different from anything expected and I think Rover T isnt being developed anymore for that reason