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you so I mean the canvas trial was set up to test the safety and efficacy of a chemical flows and in diabetes and the main manuscript itself was actually published six months ago what they described there was was an important benefit in diabetics on three point the cardiovascular mace but importantly there seemed to be a real benefit in one of the secondary endpoints which is heart failure and really this is consistent with whats being seen with some of the other sglt2 inhibitors and its really exciting from a cardiovascular perspective in a cardiologist or a clinicians perspective because diabetes heart failure is one of the biggest problems for diabetes that despite having good glucose lowering management weve not been able to previously see benefits on in terms of the heart failure effects so we then set out to really try and understand what was happening in terms of the heart failure events in this large randomized trial and what we particularly were interested in is if they ha