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Heart failure occurs when the heart is unable to pump enough blood to meet the body's needs. This can be caused by weak or damaged ventricular walls, or stiff and thickened walls that restrict blood flow. Left-sided heart failure results in inadequate oxygen-rich blood delivery, leading to fatigue and breathlessness. It also increases blood pressure in the lungs, causing fluid buildup and difficulty breathing. Right-sided heart failure impacts blood flow to the lungs, causing blood and fluid buildup throughout the body.