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[Music] hello my name is christian spalding im an interventional cardiologist and i work at the european hospital georgetown purdue in paris france and today its my pleasure to talk about the solution the noble study on behalf of the solution the noble study steering committee the solution the noble study will compare two strategies an all-deb strategy versus an rdes strategy there have been fantastic improvements in ds technology in the past years and ds are the mainstay of coronary angioplasty however ds have a two percent annual rate of tlf through five to ten years due to the presence of a metallic prosthesis which is a trigger for wrist stenosis stent thrombosis and new lesions there is therefore still room for improvement drug-coated balloons have shown their effectiveness in instantly stenosis and in small vessels but not in an all column or study if a des strategy is a non-inferior or even superior to a des strategy in an all-comer study well this could be a major breakthrou