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all right it is now my distinct pleasure to introduce the moderator of todays webinar Peyton Randolph whos a PhD student in David Luce Lab at the broad Institute of MIT and Harvard he has assisted in the initial development of prime editing and co-authored several papers in that field including the study being presented today he also called out the efforts to engineer Prime editing guide rnas or pack rnas for resistance to degradation and improved Prime editing efficiency and hes currently working on in Vivo applications for Prime editing for therapeutic benefits and this research is being supported by the National Science Foundation graduate research Fellowship and with that Peyton thank you so much for being here today and the floor is all yours well thank you uh Ronaldo for that very kind introduction and uh now for my own for our speaker today so its uh its an absolute pleasure for me to introduce now Dr uh Jordan Doman so prior to coming to Harvard for her doctoral research i