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[Music] so we are discussing series of interview questions so here comes two third question the third question is differentiate manual checks programmed checks computerize the checks ultimately cdm role is to validate the data so this will be done by performing the data review so data review will be done in order to identify the discrepant data invalid results so this data review will be done manually or it can be done programmatically if it is manually you will get many listings you can look into it and make the judgment so manual checks involve visual check of the crf with the manual review of the data for the illogical data inconsistent data so here is a good example that means manually we check the data and identify the logical and inconsistent data here is a good example so usually whenever a patient is suffering from the adverse event during the clinical trial they will be treated with the medication it is called concomitant medication so here you can see concomitant medication