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[Music] what about be angiotensin receptor net for licen inhibitors our knees thats another class of drugs were getting into some strange territory around here Cheryl Im going back to you what are they and and when do they get used right well I mean maybe I actually want to refer to the Scot on this because hes done extensive Studies on the this our knee in particular so I dont want to steal Scotts thunder no no feel free but you probably do much better than an angiotensin receptor Knepper lisen inhibitor so its a new class of drugs of course theres only one drug so far in that class and its Tsukuba trill valsartan a Tsukuba traval Sartain is essentially a compound that contains both pal Sartain which is an angiotensin receptor blocker we know it well blocks the eighty one receptor and Tsukuba trill which is a prodrug nebulizing inhibitor theyre together in a crystal essentially okay you ingest it and these come apart into the component parts so the eighty one receptor block