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The video tutorial discusses medications that should not be given to patients with heart failure, particularly focusing on those with other conditions such as diabetes mellitus. Patients with both heart failure and diabetes mellitus should not be treated with metformin or thiazolidinediones, as these medications are not allowed for heart failure patients. It is important to choose alternative anti-diabetic medications for such patients to avoid complications. It is highlighted that doctors should be cautious and opt for other medication options in these cases.