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The term spina bifida comes from the latin split spine, which is actually a pretty good description, because spina bifida is a birth defect where the tissue on the left and right side of the back that normally come over the spinal cord to protect it, dont completely meet up to form a nice seal, leaving behind various degrees of an opening right down the middle of the lower back. Very early on in fetal development, the ectoderm, which is the outer layer of the fertilized egg, starts to develop a bit of a ridge that eventually becomes the neural tube. This neural tube goes on to become the spinal cord, the brain, as well as tissues that enclose and protect them, called the meninges, and spina bifida occurs when a portion of this neural tube fails to close properly, typically in the lower back. This constitutes a defect or absence of the vertebral arches due to failure of mesoderm to organize over the region of the defect, and it may or may not involve the underlying meninges and neu