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to the modern mind many of the medical treatments of the past may seem barbaric cruel and primitive in a time when very little was understood about how the human body worked diseases were often believed to be caused by evil spirits or bad luck and treatments would often do more harm than good here are my choices for five of the most barbaric and dangerous medical practices from history number five treponation treponation is a surgical procedure in which a hole is drilled or scraped into a human skull thus exposing the brain to air in the belief that this will treat a wide variety of ailments there is evidence that treponation has been carried out since neolithic times and evidence of the practice has been found in cave paintings and at ancient burial sites those behaving abnormally might find themselves forced to have holes drilled in their heads in the belief that this will release the evil spirits causing their problems it was also used as a catch-all treatment for seizures epilepsy