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[ ♪INTRO ] From a tigers stripes, to a jaguars rosettes, to a tabbys whorls, cats come in lots of different colors and patterns. Normally, we imagine that the way an animal looks is inherited from its parents basic genetics stuff. But sometimes, the origin isnt so simple. Like, the coloring of some domestic cats is tied to their sex. Thats why orange cats are much more likely to be males, and calicos and torties are almost always female. But Siamese cats are especially interesting because their recognizable coloration is actually dependent on temperature. Animals get their dark color because their bodies produce melanin. Melanin is the same protein responsible for variation in human skin tone and making you tan. And its produced thanks in part to the enzyme tyrosinase. Normally, this enzyme does its job pretty well. But in some breeds of mouse, rabbit, and cat and even in some human cases the enzyme doesnt quite work the same. In particular, virtually all Siamese cats ha