Cut off motif in MD

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Aug 6th, 2022
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How to cut off motif in MD

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The input to the motif analysis is a set of peaks. When youre doing the motif analysis, youre trying to find if theres particular motif enriched in your set of peaks. And these motifs can be things like transcription factors or zinc finger binding proteins.
De novo sequencing refers to sequencing a novel genome where there is no reference sequence available for alignment. Sequence reads are assembled as contigs, and the coverage quality of de novo sequence data depends on the size and continuity of the contigs (ie, the number of gaps in the data).
De novo motif discovery allows you to directly query the sequence to discover which motifs are the MOST enriched sequences in your target set. Known motif discovery will simply tell you which of the known motifs is most enriched in your target set.
The position p-value is defined as the probability that a random sequence (with the same length and conforming to the background) would have a match to the motif under test with a score greater or equal to the largest found in the sequence under test.
The initial generation of the primary genetic sequence of a particular organism is called de novo sequencing. A detailed genetic analysis of any organism is possible only after de novo sequencing has been performed.
De novo gene predictors are programs that predict the exon-intron structures of genes using the sequences of one or more genomes as their only input.

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