Cut off formula in CCF smoothly

Aug 6th, 2022
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How to Cut off formula in CCF

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heart attacks are the most common cause of heart failure over time arteries can become narrowed due to the build-up of cholesterol which leads to plaque developing in the vessel wall a heart attack occurs when one of the arteries supplying blood to the heart muscle becomes either severely narrowed or blocked this means that oxygen and nourishment cant get to that part of your heart muscle causing it to die the area of dead muscle is not able to contract and so the remaining healthy heart muscle has to work harder to compensate which can lead to heart failure

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A normal level of NT-proBNP, based on Cleveland Clinics Reference Range is: Less than 125 pg/mL for patients aged 0-74 years. Less than 450 pg/mL for patients aged 75-99 years.
For people who dont have heart failure, normal BNP levels are less than 100 picograms per milliliter (pg/mL). BNP levels over 100 pg/mL may be a sign of heart failure. For NT-proBNP, normal levels are less than 125 pg/mL for people under 75 years old and less than 450 pg/mL for people over age 75.
Substantial research has shown that serum NT-proBNP level is an independent predictor of mortality in patients with sepsis [5,7,10,13,14,20], and the established cut-off value for adult patients is 4000 pg/mL [914].
A single NT-proBNP cutoff of 900 pg/mL provided similar diagnostic performance as BNP of 100 pg/mL, but age-stratified cutoff points for NT-proBNP (450 for ages 75 years) performed the best.
In terms of cardiac output, a high cardiac output state is defined as a resting cardiac output greater than 8 L/min or a cardiac index of greater than 4.0/min/m2 [1], and heart failure occurs when that cardiac output is insufficient to supply the demand.
The cut-off values of NT-proBNP and BNP for patients without acute heart failure are 125 and 35 pg/mL, respectively.
Heart failure with reduced ejection fraction (HFrEF): EF less than or equal to 40% Heart failure with preserved EF (HFpEF): EF is greater than or equal to 50%
BNP levels go up when the heart cannot pump the way it should. A result greater than 100 pg/mL is abnormal. The higher the number, the more likely heart failure is present and the more severe it is. Sometimes other conditions can cause high BNP levels.

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