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cutoff levels are used to determine whether to immediately report a negative drug test result after an initial screening or to send the specimen on to the laboratory for further confirmation testing a higher cutoff level in the screening process may cast a wider net to find the drug class being tested the confirmation test is then used as the definitive testing process to determine a positive result a screening result commonly indicates that a class of drugs is positive not necessarily which specific drug triggered the positive result confirmation testing is necessary because a false positive can occur when the screening phase is positive but the drug is not actually present a false negative can occur when the drug is actually present but the screening result is negative in order to determine if a urine specimen is negative or positive for drugs of abuse all specimens go through a screening procedure and then if initial results are above the screening cutoff levels that specimen is th
