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Dr. Kristina Butler, a gynecologic oncologist at Mayo Clinic, addresses important questions about cervical cancer. Pap smear screenings start at age 21, occurring every three to five years, depending on age. An abnormal Pap smear is common and generally indicates the need for additional tests; most individuals with abnormal results do not have cervical cancer. The HPV vaccine is now available for all adults, regardless of gender, up to age 45. It is advised to get the HPV vaccine even if one has had cervical pre-cancer or HPV exposure, as it remains beneficial in preventing further issues.