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one way a diet rich in animal sourced foods meat eggs and cheese may contribute to heart disease stroke and death is through the production of an anthro sclerosis inducing substance called TMAO and with the help of certain gut bacteria the choline and carnitine found concentrated in animal products can get converted into TMAO but wait a second I thought atherosclerosis hardening of the arteries was about the build up of cholesterol cholesterol is still king TMAO just appears to accelerate the process TMAO appears to increase the ability of inflammatory cells within the a thorough scrub in the artery wall to bind to LDL cholesterol which makes him more prone to gobble up that cholesterol so itamp;#39;s just a another piece of the puzzle of how cholesterol causes heart disease and TMAO doesnamp;#39;t just appear to worsen atherosclerosis contributing to strokes and heart attacks but also heart failure and kidney failure if you look at a really high risk group like diabetics aft