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biomarkers matter providing options for people with calangiocarcinoma every part of your body is made up of different types of cells each type of cell has distinct features molecules that can be measured in tissue blood or other bodily fluids these are called biomarkers cancer cells have damaged genes that cause the cells to go rogue this can alter the distinguishing features of these cells in various ways it can also impact how these cells operate within the body and how the body reacts in response to these rogue cells cancer biomarkers are produced either by tumor cells or by other cells in the body reacting to a tumor you might also hear them called tumor markers or driver mutations in cholangiocarcinoma cancer biomarkers may be diagnostic prognostic or predictive they each offer important clues that can help direct your care diagnostic biomarkers may signal the presence of cholangiocarcinoma prognostic biomarkers give you and your doctor a sense for how your cancer might progress a