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Flu-like symptoms can encompass a wide range of complaints, including toe pain, abdominal pain, fever, wheezing, coughing, sneezing, rhinorrhea, and headache. Patients often mention these symptoms even when seeking a prescription refill. It's important to differentiate between conditions such as upper respiratory infections, acute bronchitis, and the flu. To assess these symptoms, the speaker uses a mnemonic called "SLIT." During flu season, they emphasize the challenge of quickly determining who is genuinely sick among a crowded waiting room, fostering a sense of urgency and focused evaluation.