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Aug 6th, 2022
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How to Correct result in AFP

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[Music] hi and welcome to the doctor donovan medicine made easy youtube channel in todays video were going to be looking at alpha feta protein blood test also known as afp were going to be looking at three main things first of all what is alpha theta protein secondly why is the test used and thirdly how do you interpret the test so first of all what is afp alpha feta protein is a protein that normally is produced by the developing fetus however afp can also be produced by tumors and diseases of the liver especially hepatocellular cancer and certain testicular cancers specifically non-seminomatous germ cell tumors so why is afp requested well given this background information doctors will usually request an afp blood test if they suspect liver disease specifically liver cancer or a testicular cancer however raised afp levels dont always indicate these diseases and ill explain why in the next section of this video so what does the result mean well raised afp as already discussed is

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Normal and Critical Findings Between 15 and 20 weeks, AFP levels usually range between 10 ng/ml to 150 ng/ml.
A positive test with a high AFP suggests a birth defect like spina bifida. Thats typically a result of 2.5 times or more than the average level of AFP youd expect to see at that point in your pregnancy. A positive test with low AFP could mean a problem like Down syndrome or Edwards syndrome.
An AFP level between 0 ng/mL to 40 ng/mL is normal for adults. An extremely high level of AFP in your bloodgreater than 400 ng/mLcould be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).
AFP tests are good tools for detecting genetic disorders or neural tube defects. Up to 9 in 10 fetuses with neural tube defects were diagnosed because the AFP test detected abnormalities. But AFP tests arent perfect. In every 1,000 pregnant people who get the AFP test, up to 50 get abnormal results.
The AFP concentration in maternal serum rises throughout pregnancy, from the nonpregnancy level of 0.2 ng/mL to about 250 ng/mL at 32 weeks gestation.
Here is the normal range: For adults: less than 40 ng/mL. At 15 to 21 weeks gestation: 10 to 150 ng/mL.
An AFP level between 0 ng/mL to 40 ng/mL is normal for adults. An extremely high level of AFP in your bloodgreater than 400 ng/mLcould be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).
AFP is measured in nanograms per milliliter (ng/mL), with normal levels less than 20 ng/mL. Levels above 400 ng/mL may indicate a liver tumor or other cancer.

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