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[Music] hello Im dr. ken Landau thanks for watching lets talk about entresto entresto is a drug released by the Food and Drug Administration in 2015 to reduce the number of hospitalizations and reduce the number of people who die from cardiac disease in people who have congestive heart failure or simply heart failure treatments for the disorder have typically been an ACE inhibitor like an electro or thus in Aprill in combination with Co reg beta blocker or metoprolol and spironolactone and often times and a diuretic but sometimes people cant take the ACE inhibitor cant take the lisinopril or the enalapril because it makes them caught so they take an ARB an angiotensin receptor blocker instead a drug like diovan well heart failure is rated either class 1 2 3 or 4 this drug is for class 2 3 or 4 thats the majority of the patient class 2 people have mild symptoms they have mild shortness of breath mild angina theyre slightly limited as to their ordinary activities class 3 more sever