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Aug 6th, 2022
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How to Correct information in AFP

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[Music] hi and welcome to the doctor donovan medicine made easy youtube channel in todays video were going to be looking at alpha feta protein blood test also known as afp were going to be looking at three main things first of all what is alpha theta protein secondly why is the test used and thirdly how do you interpret the test so first of all what is afp alpha feta protein is a protein that normally is produced by the developing fetus however afp can also be produced by tumors and diseases of the liver especially hepatocellular cancer and certain testicular cancers specifically non-seminomatous germ cell tumors so why is afp requested well given this background information doctors will usually request an afp blood test if they suspect liver disease specifically liver cancer or a testicular cancer however raised afp levels dont always indicate these diseases and ill explain why in the next section of this video so what does the result mean well raised afp as already discussed is

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What does it mean if my AFP PLUS test result is screen positive? A positive AFP PLUS test means that you are in a higher likelihood group for having a baby with a neural tube defect or a chromosome abnormality. However, it does not prove by itself that there is anything wrong with the pregnancy.
Alpha-fetoprotein screening is a blood test that checks the level of alpha-fetoprotein in the mothers' blood during pregnancy. AFP is a protein normally made by the baby's liver. It is found in the fluid surrounding the baby in the womb (amniotic fluid). AFP goes through the placenta into the mother's blood.
Doctors measure AFP in your blood in nanograms per milliliter (ng/mL). The normal level for most healthy adults is between 0 and 8 ng/mL.
Higher than normal AFP levels may mean your baby has an increased risk of having a neural tube defect, such as: Spina bifida, a condition in which the bones of the spine don't close around part of the spinal cord. Anencephaly, a condition in which the brain does not develop properly.
What happens during an AFP test? A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out.
What does it mean if my AFP PLUS test result is screen positive? A positive AFP PLUS test means that you are in a higher likelihood group for having a baby with a neural tube defect or a chromosome abnormality. However, it does not prove by itself that there is anything wrong with the pregnancy.
An AFP level between 0 ng/mL to 40 ng/mL is normal for adults. An extremely high level of AFP in your blood—greater than 400 ng/mL—could be a sign of liver tumors. High levels of AFP may mean other cancers, including Hodgkin disease, lymphoma, and renal cell carcinoma (kidney cancer).
The AFP concentration in maternal serum rises throughout pregnancy, from the nonpregnancy level of 0.2 ng/mL to about 250 ng/mL at 32 weeks gestation.
AFP is a protein made by your fetus' liver. The protein passes through the placenta and into your blood. The test helps find out whether your fetus has higher than normal levels of AFP. Higher levels of AFP may mean that your fetus has an abnormality such as a neural tube defect.
The singleton pregnancy detection rates are 88% for anencephaly and 79% for open spina bifida (false-positive rate, 3%). Down syndrome risk is based on MoM values of all 5 markers and maternal age at time of delivery....Alpha Fetoprotein (AFP) Quad Screen, Penta Screen, Test Summary. DisorderNormal ScreenDown syndromeRisk <1:270Trisomy 18Risk <1:1005 more rows

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