Copy number in the suit

Aug 6th, 2022
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How to copy number in the suit

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copy number variation copy number variation abbreviated cnv refers to a circumstance in which the number of copies of a specific segment of DNA varies among different individuals genomes the individual variant may be short or include thousands of bases these structural differences may have come about through duplications deletions or other changes and can affect long stretches of DNA such regions may or may not contain a genes changes in the number of copies of small sections of our genomes can have big consequences one interesting example is a gene called amales this Gene is important for digesting starchy foods like potatoes or grains scientists found copy number variations of the amales gene in different groups of people people from places where starchy Foods were historically very important usually have more copies of the amales gene than people from backgrounds where starchy Foods were less common places where Meat and Fish were more important parts of the diet relative to starche

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Copy number variation, CNV. Changes in the number of copies of small sections of our genomes can have big consequences. One interesting example is a gene called amylase. This gene is important for digesting starchy foods like potatoes or grains.
Typically, CNV refers to germline events, which are variants in the population. CNA usually refers to somatic events, like those found in tumors. They are sometimes used interchangeably.
CNV of genomic segments are commonly found in the genomes of humans [15] and model organisms such as the mouse, the rat, or the Drosophila melanogaster fly [16]. In humans, more than 2.3 million different CNVs mapping to approximately 200,000 genomic regions have been identified so far [17].
CNVs can also encompass the repeating of whole genes within a genome. One example is the CYP2D6 gene, which codes for the cytochrome P450 in humans. P450 is an enzyme important in breaking down substances not produced by the body, including medications.
CNVs can result from structural variations within the genome including deletions, duplications, insertions or unbalanced translocations and inversions, which can lead to either a loss or gain of genomic segments.
Copy number alterations (CNAs) occur due to changes to DNA structure that lead to the gain/amplification or loss/deletion of copies of DNA sections from a normal genome.
: a numeral placed on a book to distinguish it from other copies of the same title.
Copy number variation (CNV) is a general term used to describe a molecular phenomenon in which sequences of the genome are repeated, and the number of repeats varies between individuals of the same species.

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