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copy number variation copy number variation abbreviated cnv refers to a circumstance in which the number of copies of a specific segment of DNA varies among different individuals genomes the individual variant may be short or include thousands of bases these structural differences may have come about through duplications deletions or other changes and can affect long stretches of DNA such regions may or may not contain a genes changes in the number of copies of small sections of our genomes can have big consequences one interesting example is a gene called amales this Gene is important for digesting starchy foods like potatoes or grains scientists found copy number variations of the amales gene in different groups of people people from places where starchy Foods were historically very important usually have more copies of the amales gene than people from backgrounds where starchy Foods were less common places where Meat and Fish were more important parts of the diet relative to starche