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all right so so here in the cnv workflow you see many components and our modular and white we have input and output files in gray we have functionalities that our hats that is handled by the tools and here we have box to other functionalities because this is what lies at the heart of CNB our CNB workflow now remember that I mentioned that the somatic sniffing in Dell discovery workflow doesnt call off materials agassi of us the cnv workflow is the basis for the allylic CMV workflow which can detect loss of heterozygosity events and even though i dont show a diagram here for eight cnv we will cover it at the very end so lets uh lets walk through some of the concepts behind its workflow and then we can get into the details of each of these steps this is just a reminder and I just showed this like 20 minutes ago that copy number alterations must be taken into account in conjunction with short variance and you can see how dramatic somatic copy number variation can be this these cells a