Copy number in the Detailed Medical Consent

Aug 6th, 2022
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How to copy number in the Detailed Medical Consent

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hi Im dr. ha Pinto and were going to talk today about consent and this is in continuation of our medical ethics lecture series okay so what is consent consent it defined as a permission for something to happen or an agreement to do something in the context of medicine this involves a patient providing permission or in other words consent for a treatment or an investigation gaining consent is the ethical and legal duty of that doctor okay so when a doctor requests consent from a patient this can be provided either as one written consent for example in the case of a consent form for an operation oral consent for example when were asking if we can examine a patient its imperative though that we ensure that this is documented clearly in the notes and three implied consent for example if were taking our phlebotomy equipment to the patient and they lean out their arm for us to take their blood ideally this should be avoided where possible as it may be misinterpreted by the doctor we sho

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Firstly, you can use PCR or qPCR to determine the exact number of mRNA or DNA copies, which is rather a very simple method where you generate a standard curve with a known quantity of your gene of interest and determine the copies of the target in an unknown sample. After real time PCR you will have the CT.
Copy number variation (CNV) is a phenomenon in which sections of the genome are repeated and the number of repeats in the genome varies between individuals.
NGS-Based Copy Number Analysis By providing a base-by-base view of the genome, NGS detects small or novel copy number variants that arrays often miss. NGS can also map the exact location of a CNV. The high resolution of sequencing complements the high throughput of arrays, enabling a comprehensive view of the genome.
Copy number variation, CNV. Changes in the number of copies of small sections of our genomes can have big consequences. One interesting example is a gene called amylase. This gene is important for digesting starchy foods like potatoes or grains.
Copy Number Variation Is Common in Human Genomes The schematic summarizes the distribution of insertions, deletions and inversions on each human chromosome. A total of 297 clusters were identified: 139 insertions, 102 deletions and 56 inversions breakpoints.
A variant copy is a special form of a definition copy. It creates a new, unique object. with the same attribute values as the source object.
One of the most well-known examples of a disease-causing CNV is Huntington disease, which is caused by a repeating sequence of three base pairs (known as a trinucleotide repeat) at the end of the coding region of the HTT gene.
: a numeral placed on a book to distinguish it from other copies of the same title.

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