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In the video tutorial, the presenter explains the use of droppers to apply urine samples to pregnancy tests. The top dropper contains their own urine, which has HCG since the presenter is pregnant, while the bottom dropper contains their husband's urine, which doesn't have HCG. They add three drops of each urine sample to the respective tests and wait for three minutes to interpret the results. After three minutes, they observe lines in both control areas, indicating that sufficient urine was added and the tests are functioning correctly. The presenter emphasizes not to read the results after five minutes, as they become invalid.