Conceal table in the Technology Assessment in a few clicks

Aug 6th, 2022
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How to conceal table in the Technology Assessment

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Blinding means (some) participants and investigators are not aware of which group a participant is allocated to after random allocation occurs. Allocation concealment is needed to prevent the random allocation sequence from being undermined during recruitment and treatment allocation.
The process of randomization in N-of-1 trials involves the random selection of the order of treatments for each patient. Allocation concealment is a process of concealing the allocation sequence from the investigator responsible for recruiting patients.
Some standard methods of ensuring allocation concealment include sequentially numbered, opaque, sealed envelopes (SNOSE); sequentially numbered containers; pharmacy controlled randomization; and central randomization.
Allocation concealment is a technique used to prevent selection bias by concealing the allocation sequence from those assigning participants to intervention groups, until the moment of assignment ().
Concealment of allocation is done as the participant enters the trial. Concealment secures randomization and prevents selection bias. Every researcher tries to prove his hypothesis as correct.
Allocation concealment is a different concept to blinding. It means that the person randomising the patient does not know what the next treatment allocation will be. It is important as it prevents selection bias affecting which patients are given which treatment (the bias randomisation is designed to avoid).
Allocation concealment is the technique of ensuring that implementation of the random allocation sequence occurs without knowledge of which patient will receive which treatment, as knowledge of the next assignment could influence whether a patient is included or excluded based on perceived prognosis.
This is random allocation, or random assignment, and all the methods used for random selection can be used for random allocation. For example, a pharmacy company may choose every other name on its sample list to choose who gets the new medication and who gets the placebo (systematic).

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