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Iamp;#39;m John Alexander. Iamp;#39;m a Cardiologist and Professor of Medicine from Duke University in North Carolina in the United States. Factor XI inhibitors are a new class of drugs that inhibit one factor, factor XI, in the coagulation pathway and theyamp;#39;re really new. And thereamp;#39;re about four or five of them that are in development. Asundexian, which is being developed by Bayer, is one of them. And thatamp;#39;s what we studied in Pacific AMI. And the hope is that they will have some advantages over existing antithrombotic drugs, like aspirin, like the P2Y12 inhibitors, clopidogrel, ticagrelor and prasugrel, and like other anticoagulants, like vitamin K antagonists or warfarin and rivaroxaban, that have limitations, that have benefits but also have limitations in patients after an acute myocardial infarction. So we like to lump all anticoagulants together but theyamp;#39;re really different. So factor XI is in the contact activation pathway and asundexian inhibit
