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I have discussed the utilization of Delta s cvo2 for the determination of fluid responsiveness in the past thankfully thereamp;#39;s a new systematic review and meta-analysis that looks at using this parameter these data are free for you to download up to the authors they analyze 240 patients over five observational trials they found that Delta s cbo2 was excellent to predict fluid responsiveness the area under the receiver operating curve was 0.86 this is considered to be excellent although gold standard type tests have an area under the curve greater than 0.9 the mean cutoff for Delta scb02 was greater than four percent if the Delta scv02 is greater than four percent then the patient is fluid responsive one of the caveats is that all these patients were on mechanical ventilation but the biggest caveat is that most blood gas analyzers have that four percent within their margin of error will this change your practice
