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When dealing with a large Excel file, particularly with only two sheets and minimal data, consider optimizing performance by removing unused formatting and metadata. In Excel on the web, go to Review Check Performance to see suggestions for optimizing your workbook. You can individually optimize each sheet or use the Optimize All feature to remove unnecessary elements without deleting important data. This process can significantly reduce the file size, like in this example where a 4.9 megabyte file was reduced to 46 kilobytes.