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In this course, Karen, a self-taught iOS developer, will guide absolute beginners through the basics of the Combine framework, which she has extensively used since its announcement in 2019. The course starts with the fundamentals of subscriptions, covering how to create a data stream from passing values and how to cancel it if necessary. Participants will learn about various subscribers, including assign and sync, highlighting Combine's strength in asynchronous programming. Additionally, the course will touch on multi-threading, explaining how to change threads within data streams, switch to a background thread, and return to the main thread.