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In this video tutorial, Carla discusses the key questions to ask during a subjective examination, focusing on past medical history, drug history, and social history. The acronym "hashtag Thread Sox" is used to remember important conditions to inquire about, including fractures, thyroid conditions, heart conditions, rheumatoid conditions, epilepsy, asthma, diabetes, previous steroid use, osteoporosis, cancer history, and history of surgery. These categories are crucial in gathering thorough patient information.