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Dr. Rishi Desai from Osmosis shares three tips for taking an effective patient history. He emphasizes that while the mechanics involve gathering details such as the chief complaint, History of Present Illness (HPI), past medical history, medications, allergies, family history, social history, and review of systems, the key to success lies in how the information is gathered. His first tip is to listen well and empathize with the patient, highlighting the importance of human connection in understanding their concerns, as patients could otherwise seek information from automated sources.