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so hello and welcome to todays webinar clinical trial design trends for 2022 and obviously giving a preview here of what those trends well be talking about today platform trials prediction models and non-proportional hazards in survival trials so todays webinar will kind of be a grab bag of some interesting areas where things definitely have happened a lot in these areas over the last couple of years but i think in 2022 you might see some you know big decisions big choices and big proliferation of these ideas um in the clinical trial space and beyond before we get started just a few frequently asked questions firstly is this webinar being recorded yes and the recording will be sent to you after this webinar is complete probably just an hour or two after were done here alongside the slides that im using here today the other questions are usually about how to give me feedback you can give feedback during the webinar by selecting the question uh tab on the right hand side of your we