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the endometrium is the inside lining of the uterus an endometrial biopsy is the removal of a sample of tissue from the endometrium for testing a biopsy may be done to screen for cancer or precancerous cells to determine the cause of irregular bleeding or to investigate fertility problems this procedure can also check for infections and monitor the effectiveness of certain medications an endometrial biopsy can be done in your doctors office in 10 to 15 minutes without the use of a sedative your doctor will first do a manual exam to determine the position of your uterus and then place a speculum in your vagina to open it up and keep it open so the cervix is visible your doctor may use another instrument called a tenaculum to grasp the cervix and hold it steady during the procedure your doctor will then pass a long thin flexible tube called a pipe health through your vagina and cervix and into your uterus the pipe L is equipped with a piston like device that creates suction when pulled
