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Health Technology Assessments (HTAs) are systematic evaluations that examine the clinical, economic, and social implications of healthcare technologies, including drugs, medical devices, and diagnostic tests. They aid decision-making regarding the adoption and use of these technologies. HTAs analyze evidence related to safety, efficacy, and cost-effectiveness, while also considering patient outcomes, ethical and social implications, and feasibility of implementation in healthcare settings. Various stakeholders, including policymakers, healthcare providers, and patients, utilize HTAs to inform decisions on healthcare technologies. This tutorial is sponsored by Nested Knowledge, a platform that supports systematic literature review and meta-analysis.