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Health technology assessments (HTAs) are systematic evaluations of the clinical, economic, and social implications of healthcare technologies, including drugs, medical devices, and diagnostic tests. They inform decision-making regarding the adoption and use of these technologies. HTAs involve reviewing evidence related to safety, efficacy, and cost-effectiveness. Additionally, they consider patient outcomes, ethical and social implications, and feasibility of implementation in healthcare settings. Various stakeholders, including policymakers, healthcare providers, and patients, utilize HTAs for guidance on healthcare decisions. This tutorial is sponsored by Nested Knowledge, a platform specializing in systematic literature reviews and meta-analysis.