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When assessing a patient who feels unwell, you can use the mnemonic SAMPLE: S stands for Signs and Symptoms, A for Allergies, M for Medications, P for Pre-existing conditions, L for Last meal, and E for Events leading to the current situation. The patient's age influences your approach; speak directly to adults, while with children, engage parents or guardians for additional insights and adjust your communication to be more understandable and less frightening for the child. Signs are observable issues, while symptoms are reported by the patient. This structured approach aids in gathering essential information for further action or for informing emergency medical services and family members.