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five alarming signs of motor neuron disease recognizing early signs of mnd is crucial for timely diagnosis and intervention here are five alarming symptoms that may indicate the presence of mnd progressive muscle weakness one of the earliest and most prominent signs of mnb is gradual muscle weakness it typically starts in one region such as the hands arms legs or voice and progresses over time muscle twitching and cramps persistent muscle twitching in cramps especially in combination with weakness can be warning signs of mnd these involuntary muscle movements often occur in affected areas and may become more frequent as the disease progresses difficulty in swallowing mnd can impact the muscles responsible for swallowing individuals may experience difficulty in swallowing food and liquids increasing the risk of choking or aspiration changes in speech and voice slurred speech or a noticeable change in voice quality can be alarming symptoms of MNT individuals may have difficulty articulat
