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A food allergy is a medical condition characterized by an abnormal immune reaction to certain foods. The most common allergens are the "big eight": milk, eggs, peanuts, tree nuts, seafood, shellfish, soy, and wheat. Typically, food does not provoke allergies due to a process called oral tolerance. In a normal digestive process, food proteins are broken down in the stomach and intestines into small fragments called oligopeptides. These oligopeptides interact with Payer's patches, tissue areas in the intestinal wall that contain specialized immune cells known as M cells.