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A pilot study is investigating potential changes to blood donor eligibility for gay men, with Florida-based One Blood participating. Current policy requires a 3-month wait between donations for men who have sex with other men, but the study may alter this based on individual risk assessments for HIV. This groundbreaking study could lead to a shift in criteria, assessing donors based on personal risk rather than the timing of their last sexual contact. One Blood is collaborating with community outreach centers in South Florida for this research.