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Medication administration nurses are crucial in preparing, administering, and evaluating medication effects on clients. They also educate on medication side effects, adherence, and ability to self-medicate. Understanding medication regulations is key in ensuring client safety. The Pure Food and Drug Act of 1906 was the first American law regulating medications, with federal laws now extensively controlling medication sales, distribution, testing, labeling, and controlled substances. State and local laws must comply with federal regulations, with state laws governing substances not federally regulated and local laws overseeing alcohol and tobacco use. Policies are in place to prioritize client well-being.