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Welcome all of you from across the world to NICEs webinar in a series of webinars in which were talking you through the changes were making to our process and methods for health technology evaluation at NICE. My name is Meindert Boysen, I am the director for the centre for health technology evaluation and also NICEsdeputy chief executive. A couple of housekeeping notes, we are recording this webinar and you willfind a recording later, together with the slides, and other recordings or webinars wevealready done in this series on our website. We will be using a formal set of presentations in three parts, there will be an introduction, a scope, and a presentation on the specifics of the proposals, and the slides will be available after meeting as I said. Most of the meeting today will be dedicated to a QA (question and answer) and this will involve a panel that will introduce in a minute, and the QA again will be in two parts the first part we will be
