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A food allergy is a medical condition where there's an abnormal immune reaction to certain foods. The most common allergens are known as the big eight, including proteins from milk, eggs, peanuts, tree nuts, seafood, shellfish, soy, and wheat. Normally, food doesn't cause allergic reactions due to oral tolerance. Proteins in food are broken down into oligopeptides by gastric acid and proteases in the stomach and intestines. These oligopeptides reach the payer's patches, where M cells reside. For more information, watch the full video on osmosis.org.