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syphilis is a sexually transmitted disease caused by the bacterium treponema pallidum the exact origin of Syphilis is still a topic of debate among researchers but it is generally agreed that the disease first appeared in Europe in the late 15th century one popular theory is that syphilis was brought to Europe by Christopher Columbus and his crew during their return from the new world in 1493. ing to this Theory the disease was already present among the native peoples of the Americas and Columbus and his crew contracted it while there however there is no conclusive evidence to support this Theory and many researchers believe that syphilis was already present in Europe before Columbuss return some historical documents describe symptoms that resemble those of syphilis dating back to the 13th century and skeletal remains from Europe and Africa that predate Columbuss Voyage have also shown evidence of the disease regardless of its origin syphilis spread rapidly throughout Europe in the 1