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The skin covers the body and protects it from the external environment. It also prevents water loss, provides sensory function, plays a role in body temperature regulation, and is the site of vitamin D synthesis. The skin is composed of 2 layers: the outer epidermis and the deeper dermis. The dermis is connected to underlying structures via a subcutaneous tissue, the hypodermis, which is not technically considered part of the skin. The epidermis provides barrier and protection, it consists mainly of the protein keratin, a tough and water-insoluble structural protein. The dermis constitutes the bulk of the skin, it provides support and flexibility. The dermis consists mainly of collagen, and to a lesser extent, elastin fibers. Loss of collagen and elastin, such as with aging, causes the skin to slack. The boundary surface between the epidermis and dermis is not flat but wavy, meaning the 2 tissues interlock, strengthening their connection. With age, this boundary flattens and the skin b
