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hi so this module were going to be talking about signal noise and bold physiology so to recap MRI studies brain anatomy here we take structural images or t1-weighted images typically and these images have high spatial resolution and can thus be able to distinguish between different types of tissue so in the example we see here we see that were able to make it you know were able to differentiate between different tissue types functional magnetic resonance imaging studies brain function here we take functional images or t2 star awaited images they have lower spatial resolution but higher temporal resolution so we have multiple lower temporal resolution scans acquired rapidly here we can relate changes in signal to experimental manipulations so an fMRI experiment consists of a sequence of individual MRI images where one can study oxygenation patterns in the brain across time so here we see a series of brain images that have been acquired and lets say that we look at a single voxel of